5-(2-THIENYL)-3-PYRAZOLECARBOXYLIC ACID

5-(2-THIENYL)-3-PYRAZOLECARBOXYLIC ACID - Names and Identifiers

Name	5-THIEN-2-YL-4H-PYRAZOLE-3-CARBOXYLIC ACID
Synonyms	AKOS PAO-0367 5-(2-THIENYL)PYRAZOLE-3-CARBOXYLIC ACID 5-(2-THIENYL)-3-PYRAZOLECARBOXYLIC ACID 5-THIEN-2-YL-1H-PYRAZOLE-3-CARBOXYLIC ACID 5-THIEN-2-YL-4H-PYRAZOLE-3-CARBOXYLIC ACID 5-(thiophen-2-yl)-1H-pyrazole-3-carboxylate 5-THIOPHEN-2-YL-1H-PYRAZOLE-3-CARBOXYLIC ACID 1H-Pyrazole-3-carboxylic acid, 5-(2-thienyl)- 3-(thiophen-2-yl)-1H-pyrazole-5-carboxylic acid 5-(Thiophen-2-yl)-1H-pyrazole-3-carboxylic acid
CAS	182415-24-3
InChI	InChI=1/C8H6N2O2S/c11-8(12)6-4-5(9-10-6)7-2-1-3-13-7/h1-4H,(H,9,10)(H,11,12)/p-1

5-(2-THIENYL)-3-PYRAZOLECARBOXYLIC ACID - Physico-chemical Properties

Molecular Formula	C8H6N2O2S
Molar Mass	194.21
Melting Point	226 - 227℃
Boling Point	509.4°C at 760 mmHg
Flash Point	261.8°C
Vapor Presure	3.38E-11mmHg at 25°C
Appearance	Pale yellow
Storage Condition	Room Temprature

5-(2-THIENYL)-3-PYRAZOLECARBOXYLIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29331990
Hazard Note	Irritant

5-(2-THIENYL)-3-PYRAZOLECARBOXYLIC ACID - Introduction

ACID is an organic compound with the chemical formula C10H6N2O2S. It has the following properties:

Nature:
1. Appearance is white to yellow crystalline state;
2. Soluble in some organic solvents such as ethanol and dimethyl sulfoxide, slightly soluble in water;
3. It will decompose at high temperature.

Use:
1. ACID can be used as various chemical reagents and synthetic intermediates;
2. In organic synthesis, it can be used to synthesize compounds containing thiophene and pyrazole groups;
3. Can be used for the synthesis of electrochemical ceramics and photoelectric materials.

Method:
The ACID preparation method can be carried out through the following steps:
1. Mixing pyrazolone and acetic anhydride, and carrying out esterification reaction at room temperature;
2. Adding thiophene and catalyst to carry out substitution reaction;
3. After oxidation and acid hydrolysis treatment to obtain the product.

Safety Information:
The following safety precautions should be taken when handling the IP ID:
1. Wear appropriate protective clothing and gloves to avoid direct contact with skin and eyes;
2. Operate in a well-ventilated place to avoid inhaling the generated gas, steam and dust;
3. Comply with the correct laboratory operating procedures and safety operation guidelines;
4. Should be stored away from the fire and oxidant.

Last Update：2024-04-10 22:29:15